The labyrinth of hormonal imbalances and peptide therapy requirements demands precision, and this precision is delivered through advanced laboratory tests. As healthcare moves towards a more personalized approach, the spotlight is on intricate tests that facilitate effective patient treatments. These diagnostic measures ensure that interventions are tailored to individual needs, maximizing therapeutic benefits and minimizing risks. Dive into the intricacies of the diverse lab tests backed by professionals like Dr. George Shanlikian, M.D, that support hormone and peptide therapies.

Serum Hormone Panels

The gold standard in hormonal testing, serum hormone panels measure the levels of various hormones in the blood. These tests provide a snapshot of the body’s hormonal milieu and are crucial for assessing imbalances related to conditions like hypothyroidism, menopause, and androgen deficiency.

  • Key Hormones Measured: Thyroid hormones (T3, T4, TSH), s*x hormones (estrogen, progesterone, testosterone), and adrenal hormones (cortisol, DHEA)

Salivary Hormone Testing

Offering a non-invasive approach, salivary hormone tests evaluate bioavailable hormone levels—the hormones that are free and functionally active. Professionals often recommend this test for its ability to capture daily hormonal fluctuations, which is especially useful for assessing adrenal function and circadian rhythm disorders.

  • Applications: Diagnosing adrenal fatigue, pinpointing ovulation, and assessing stress responses

Urinary Hormone Metabolites

Urine tests delve deeper by analyzing hormone metabolites. These tests offer insights into how the body processes and excretes hormones, giving healthcare professionals information on hormonal pathways and potential metabolic dysfunctions.

  • Insights Gained: Estrogen metabolism patterns, DHEA metabolic pathways, and melatonin breakdown

Peptide Mapping and Analysis

Peptides, small chains of amino acids, play crucial roles in various bodily processes. Peptide therapies have emerged as innovative treatments for various conditions, from growth hormone deficiencies to immune disorders. Laboratory analysis of peptide levels and functions ensures that therapies are designed for optimum efficacy.

  • Use Cases: Evaluating growth hormone-releasing peptides (GHRPs), monitoring therapeutic peptides like BPC-157, and analyzing peptide receptor functions

Comprehensive Metabolic Panels (CMP)

While not exclusively a hormone test, CMPs offer a broad view of the body’s metabolic status. By examining various markers, from liver enzymes to blood sugar, professionals gain insights that can indirectly hint at hormonal issues.

  • Markers Evaluated: Electrolytes, kidney function (BUN, creatinine), glucose, liver enzymes (ALT, AST), and protein levels

Genetic Testing for Hormonal Receptors

Advancements in genetics have enabled professionals to examine genes responsible for hormone receptors. Such tests help understand individual sensitivities, responsiveness, and potential risks associated with hormone and peptide therapies.

  • Applications: Predicting breast cancer risks due to estrogen receptor mutations, assessing testosterone receptor sensitivities, and tailoring peptide therapies based on genetic profiles

Functional Medicine Testing

Beyond mere numbers, functional medicine tests focus on how the body’s systems interact and function. They offer comprehensive insights into hormonal health by analyzing many markers, from nutrient levels to gut health, as each can influence hormonal balance.

  • Key Insights: Gut-hormone connection, nutrient imbalances affecting hormonal pathways, and underlying chronic conditions influencing hormonal health


The field of hormone and peptide therapies is intricate and vast. Ensuring these therapies yield the desired results without adverse effects necessitates a thorough and multifaceted diagnostic approach. As highlighted above, the bevy of lab tests backed by seasoned professionals like Dr. George Shanlikian, M.D, stands testament to the rigorous scientific processes underscoring these interventions. As humans continue to advance in the realms of personalized medicine, these diagnostic marvels will undoubtedly remain pivotal, sculpting a path toward holistic, precise, and transformative care.



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